|Introduced In||Not in Portland|
|Owned By||Miami Central University Medical Research Laboratory|
|Found By||Juliet Burke|
A4993-E3 is the name of a test drug which Juliet was using to perform fertility tests on her sister Rachel. She had obtained the drug by stealing samples from her ex-husband, Edmund Burke's, laboratory. It seems that this drug was in fact successful as Juliet's sister revealed she was pregnant and that the tests did work.